Metabolic Systems Biology

University of California, San Diego

The Metallo laboratory at UCSD applies a multi-disciplinary approach to understand how metabolism contributes to disease. We incorporate analytical chemistry, mass spectrometry, cell biology, and systems-based modeling to study metabolic regulation in cells, tissues, and animals. We integrate the use of stable isotope tracers and engineering principles to quantitatively describe how metabolic function (or dysfunction) contributes to human disease.